[关键词]
[摘要]
糖尿病已成为威胁人类生命健康的第3大杀手,其发生发展与肠道菌群失调引起的系列变化密切相关。因此调整肠道菌群结构成为治疗糖尿病的新思路。中药防治糖尿病取得了较好疗效,改善肠道菌群结构可能是其重要机制之一。对基于肠道菌群新靶点的中药单体成分(小檗碱、根皮苷、大黄酸等),中药单方(肉桂精油、黄连花薹、前胡总香豆素等)和中药组方(葛根芩连汤、升降散、补中益气汤等)防治糖尿病研究进展进行综述,为糖尿病防治药物的开发及防治方法与思路提供参考。
[Key word]
[Abstract]
Diabetes has become the third largest killer to human life and health, and its development is closely related to the intestinal flora imbalance caused by series of consequences. So adjusting the structure of intestinal flora becomes a new idea for the treatment of diabetes. Traditional Chinese medicine (TCM) has good curative effect in prevention and treatment of diabetes, and improvement on the structure of intestinal flora may be one of its important mechanisms. The article reviewed the research progress on prevention and treatment of diabetes by TCM single components (berberine, phloridzin, rheinic acid, etc), TCM single prescription (essential oil from Cinnamomum cassia, flower stalk of Coptis chinensis, total coumarin of Feucedani Radix) and TCM priscriptions (Gegen Qinlian Decoction, Shengjiang Powder, Buzhong Yiqi Decoction, Huanglian Jiedu Decoction, Wenyang Yiqi Huoxue Compound, etc.) based on new targets in intestinal flora, so as to provide reference for the development of TCM for prevention and treatment of diabetes.
[中图分类号]
[基金项目]