目的 建立用电感耦合等离子体发射光谱法（ICP-OES）测定右旋糖酐铁中铅、镉、砷、汞、钴、钒、硒、钼8种重金属元素含量的分析方法。方法 通过检测波长考察，仪器参数优化，验证基体效应干扰，考察内标物校正干扰，测定8种重金属元素的含量。结果 内标法校正基体效应干扰，待测元素回收率由83%~90%提高为94%~100%，方法准确度良好，加标回收率在94.3%~101.5%，方法精密度良好（RSD<3.5%，n=6）。各待测元素线性关系良好，相关系数均大于0.999，检出限为0.22~8.54 ng/mL，定量限为0.68~25.73 ng/mL。结论 方法准确度高、灵敏度高、迅速可靠，可用于右旋糖酐铁中8种重金属元素含量的测定。

Objective To establish a method for the determination of 8 heavy metal elements of Pb, Cd, As, Hg, Co, V, Se, Mo in iron dextran by inductively coupled plasma optical emission spectrometry (ICP-OES). Method Through selection of detection wavelengths, optimization of instrument parameters, verification of matrix effect interference and investigation of internal standard for correction of matrix effect interference, the 8 heavy metal elements were analyzed by ICP-OES. Results The recovery rate of the detected elements were increased from 83%-90% to 94%-100%, after correction of matrix effect interference by internal standard method. The accuracy of the method were good. The spiked recoveries of the detected elements were from 94.3% to 101.5%. The precision of the method were good (RSD<3.5%, n=6). The linearities of the detected elements were good, and the correlation coefficients were all greater than 0.999. The detection limits were from 0.22 to 8.54 ng/mL. The quantization limits were from 0.68 to 25.73 ng/mL. Conclusion The established method was accurate, sensitivity, rapid and reliable, which can be applied to the determination of contents of 8 heavy metal elements in iron dextran.