[关键词]
[摘要]
丹参多酚酸为丹参的水溶性提取物,具有清除自由基、保护脑神经细胞、改善脑部血液循环、改善抑郁症认知障碍、抗炎、抗肿瘤等药理作用。相较于化学成分与药理作用,目前对其制备工艺的研究相对较少。主要综述丹参多酚酸的分析方法、提取纯化工艺等研究进展,以期为深入研发提供参考。丹参多酚酸主要采用的分析方法有紫外分光光度法、近红外光谱法、一测多评法、比色法等;提取工艺主要为加热回流提取、温浸法、渗漉法、酶法提取等;纯化工艺为大孔吸附树脂纯化法、ZnCl2沉淀法、超滤法等。
[Key word]
[Abstract]
Salvianolic acid is the water soluble extract of Salvia miltiorrhiza, and it can improve the blood circulation of the brain and improve the cognitive disorder of depression, anti-inflammation, anti-tumor and so on. At present, the research on its technology is relatively less. This particle will mainly review the research progress of analytical methods, extraction and purification technology of salvianolic acids. The main analysis methods used for salvianolic acids include UV spectrophotometry, near-infrared spectroscopy, quantitative analysis of multi-components by single marker (QAMS), colorimetry and so on. The extraction process is mainly heating reflux extraction and warm soaking method, percolation method, enzymatic extraction, etc. The purification process is macroporous resin purification, ZnCl2 precipitation method, ultrafiltration and so on.
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