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[摘要]
目的 建立用电感耦合等离子体发射光谱法(ICP-OES)测定右旋糖酐铁中铅、镉、砷、汞、钴、钒、硒、钼8种重金属元素含量的分析方法。方法 通过检测波长考察,仪器参数优化,应用干扰元素校正法(IEC)校正光谱干扰,测定8种重金属元素的量。结果 应用IEC法校正光谱干扰,回收率在88.7%~101.3%之间,方法准确度良好,各待测元素线性关系良好,相关系数均大于0.999,检出限为0.12~7.26 ng/mL,定量限为0.40~23.96 ng/mL,方法精密度良好(RSD<3.5%,n=6)。结论 应用IEC法进行光谱校正后的结果明显优于未加校正的常规法测定结果。建立的方法准确、灵敏、迅速,可用于右旋糖酐铁中8种重金属元素含量的测定。
[Key word]
[Abstract]
Objective To establish a method for the determination of eight heavy metal elements (Pb, Cd, As, Hg, Co, V, Se, and Mo) in iron dextran by inductively coupled plasma optical emission spectrometry (ICP-OES). Methods Through detection wavelength selection, optimization of instrument parameters and applying interference element correction (IEC) method to correction of spectral interference, the eight heavy metal elements were analyzed by ICP-OES. Results The elements recoveries were from 88.7% to 101.3% by correction of spectral interference with IEC method. The accuracy of the method was good. The linearities of the detected elements were good, and the correlation coefficients were all greater than 0.999. The detection limits were from 0.12 to 7.26 ng/mL. The quantization limits were from 0.40 to 23.96 ng/mL. The precision of the method was good (RSD<3.5%, n=6). Conclusion The results of the spectral interference correction by IEC method are greatly superior to the results of conventional method. The established method is accurate, sensitive, and rapid, which can be applied to the determination of contents of eight heavy metal elements in iron dextran.
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