[关键词]
[摘要]
目的 了解冠心宁注射液近10年来的临床应用与不良反应情况。方法 以"冠心宁注射液"为检索词,检索2005年1月-2015年9月中国期刊全文数据库(CNKI)和中国生物医学文献数据库(CBM)中收录的有关文献,回顾性分析其临床疗效、适用病症、不良反应、使用剂量等。结果 共纳入254篇11558例患者参加的研究报道,该药用于治疗循环系统、呼吸系统、泌尿系统等多种疾病,83例出现不良反应,其中21例为过敏反应,其他不良反应程度较轻。结论 冠心宁注射液的临床疗效较为显著,不良反应发生率低,而且程度轻。
[Key word]
[Abstract]
Objective To investigate the clinical applications and adverse responses of Guanxinning Injections. Methods Searched the China national knowledge infrastructure (CNKI) and Chinese biomedical literature database (CBM) with the key word "Guanxinning Injection" from January 2005 to September 2015, and then retrospectively analyzed the clinical effects, side effects, doses of drugs, as well as diseases that the injection treated. Results 254 relative articles were involved, including 11 558 patients. There were 21 cases with allergic reactions, and other low-degree adverse effects. Conclusion Guanxinning Injection has dramatic clinical effects with low incidence of adverse reaction, but attention paid to the safety evaluation of Guanxinning injection is not adequate.
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