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[摘要]
目的 探讨苯磺酸左旋氨氯地平治疗高血压的临床效果。方法 124 例高血压患者随机分为对照组与治疗组,每组62 例。对照组给予硝苯地平缓释片10 mg/次,2 次/d;治疗组给予苯磺酸左旋氨氯地平2.5 mg/次,1 次/d,两组患者均治疗12 周,比较两组的治疗效果及治疗前后血压变化及不良反应发生情况。结果 治疗组总有效率为93.5%,明显高于对照组的80.6%,不良反应发生率为4.8%,明显低于对照组的16.1%,两组比较差异显著(P< 0.05);治疗后,治疗组舒张压、收缩压优于对照组,且差异显著(P< 0.05)。结论 苯磺酸左旋氨氯地平治疗高血压的临床效果显著,可有效改善患者临床症状,降低患者血压,安全性高,不良反应少,是治疗高血压的理想选择。
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[Abstract]
Objective To explore clinical efficacy of Levamlodipine Besylate Tablets for the treatment of hypertension. Methods One hundred and twenty-four patients with hypertension were selected as research subjects, who were divided into the control group and the observation group with 62 cases in each group according to different treatment methods. Patients in the control group were subjected to the treatment of Sustained-release Nifedipine Tablets, and patients in the observation group were subjected to the treatment of Levamlodipine Besylate Tablets, the treatment efficacy and the change in blood pressure and the occurrence of adverse reaction of patients before and after treatment were compared and analyzed. Results The total effective rate of treatment for patients in the observation group was 93.5%, being significantly higher than that in the control group at 80.6%, and the incidence of adverse reactions of patients in the observation group was 4.8%, being significantly lower than that in the control group at 16.1%, with significant difference (P <0.05). Diastolic blood pressure and systolic blood pressure of patients in the observation group after treatment were better than those in the control group, and the difference was significant (P <0.05). Conclusion Levamlodipine Besylate Tablets delivers significant efficacy in the treatment of hypertension, it can effectively improve clinical symptoms of patients, reduce the blood pressure of patients, and it is an ideal choice for the treatment of hypertension with high safety and less adverse reaction, being worthy of popularization.
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