目的 对河北省沧州中西医结合医院口服抗高血压药物的临床应用情况进行分析, 为合理用药提供参考。方法 对该院2011年1月－2013年12月门诊口服抗高血压药的品种、销售额、用药频度(DDDs)等进行统计分析。结果 3年里该院口服抗高血压药的销售额和用药频度显著上升, 以钙通道阻滞剂类、血管紧张素转换酶抑制剂类、血管紧张素Ⅱ受体拮抗剂类为主, 单用品种DDDs排名前3位的依次是氨氯地平、硝苯地平、吲达帕胺。结论 该院口服抗高血压药应用情况基本合理。

Objective To investigate and analyze the application condition of oral antihypertensive drugs in Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine of Hebei Province, and to provide the basis for clinical treatment. Methods The application conditions of oral antihypertensive drugs in the hospital were evaluated in the aspect of drug classification, sales amount, and defined daily dose system (DDDs) from January 2011 to December 2013. Results In recent three years, the consumption sum and DDDs of oral antihypertensive drugs were significantly increased in the hospital, especially the calcium channel blockers, angiotensin converting enzyme inhibiton, and angiotensin Ⅱ receptor antagonists. The top three oral antihypertensive drugs were Amlodipine, Nifedipine, and Indapamide in the term of DDDs. Conclusion The application of oral antihypertensive drugs is reasonable in outpatient in the hospital.

沧州市科技计划项目(131302026)