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[摘要]
目的 建立柴芩清热胶囊的质量控制方法。方法 采用薄层色谱(TLC)法对组方中柴胡、连翘、诃子、大黄进行定性鉴别,采用高效液相色谱(HPLC)法测定黄芩苷。结果 薄层色谱清晰,分离良好,阴性无干扰。黄芩苷定量测定的平均回收率为98.39%,RSD为0.81%。结论 该方法简便易行、灵敏准确、专属性强,可用于柴芩清热胶囊的质量控制。
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[Abstract]
Objective To establish the quality control method of Chaiqin Qingre Capsules. Methods Bupleuri Radix, Forsythiae Fructus, Chebulae Fructus, and Rhei Radix et Rhizoma in the prescription were identified by thin layer chromatography (TLC);The baicalin content was quantitatively determined by high performance liquid chromatography (HPLC). Results The spots from the test solutions on the thin layer plate were clear and well separated without the negative interference. The average recovery rate of paeoniflorin was 98.39%, RSD was 0.81%. Conclusion This method is simple to operate, sensitive and accurate with strong specificity, which can be used to control the quality of Chaiqin Qingre Capsules.
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