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[摘要]
目的 优选益气养心颗粒中丹参提取工艺。方法 以丹参酮ⅡA、丹酚酸B的提取量和提取液浸膏得率为考察指标,采用正交设计,考察溶剂用量、提取次数、提取时间等对提取效果的影响。结果 最佳提取工艺为用10倍量的50%乙醇提取3次,每次1 h。结论 优选的纯化工艺简单易行,适用于实际生产。
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[Abstract]
Objective To optimize the extraction technology of Salvia Miltiorrhizae Radix et Rhizoma in Yiqi Yangxin Granule. Methods Using orthogonal test design, the effects of solvent amount, extracting times and extracting time on extraction were investigated using the amounts and extract yields of tanshinone IIA and salvianocilic acid B as indexes. Results The optimum extraction parameters were as follow: 10 times of 50% ethanol, extracting for 3 times and 1 h each time. Conclusion The purification process is simple and suitable for practical production.
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