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[摘要]
目的 建立了祛毒清热颗粒的质量标准。方法 采用薄层色谱法对方中的连翘、柴胡、甘草、板蓝根进行定性鉴别,采用高效液相色谱法对君药虎杖中的大黄素进行了定量测定。结果 薄层分离度好,专属性强;大黄素在0.064~0.512 μg内与峰面积线性关系良好,平均回收率为99.03%,RSD值为0.23%(n=9)。结论 所建立的方法准确可靠,灵敏度高,专属性强,可有效控制祛毒清热颗粒的质量。
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[Abstract]
Objective To establish the quality standard for Qudu Qingre Granule (QQG). Methods TLC method was performed to identify Forsythiae Fructus, Bupleuri Radix, Glycyrrhizae Radix et Rhizoma, and Isatidis Radix in QQG and HPLC was used to determine the content of emodin in sovereign medicine—Polygoni Cuspidati Rhizoma et Radix. Results TLC had good resolution and specificity. The emodin showed a good linear relationship within the range of 0.064 — 0.512 μg. The average recovery rate was 99.03% with RSD of 0.23% (n = 9). Conclusion The method is accurate, specific, and could be used for the quality control of QQG.
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