[关键词]
[摘要]
目前药动学研究方兴末艾,国内对药动学技术要求越来越高。综述了外用制剂的药物吸收、分布、代谢和排泄等过程各自的研究进展;对外用制剂的应用现状和代谢特点进行了介绍,重点归纳了药物有效成分的药动学研究方法和检测技术。同时还指出药动学研究的重要性和今后外用制剂药动学研究中应该解决的问题。
[Key word]
[Abstract]
At present, pharmacokinetic research is still at the exploratory stage, and the domestic demand for pharmacokinetic technique is increasing. The research progress on drug absorption, distribution, metabolism, and excretion of external preparation were reviewed; Application status and metabolic characteristics of external preparation were introduced; And the pharmacokinetic study and detection methods of effective ingredient were mainly summarized. At the same time, the paper also pointed out the importance of future pharmacokinetic studies and the problems to be solved.
[中图分类号]
[基金项目]
福建省科技重大专项(2009YZ0001-1-3);福建省医学创新项目(2009-CX-16);福建省省属公益类科研院所基本科研专项(2011R1034-3)