[关键词]
[摘要]
目的 研究雷公藤内酯醇生物贴中雷公藤内酯醇在不同条件下的稳定性。方法 通过影响因素试验、加速试验、长期留样试验,采用高效液相色谱法,测定雷公藤内酯醇,考察雷公藤内酯醇生物贴的稳定性。结果 经过光照、升温、加湿、加速等试验,雷公藤内酯醇生物贴中的雷公藤内酯醇的量变化不大。结论 雷公藤内酯醇生物贴在市售包装及贮藏条件下,质量稳定。
[Key word]
[Abstract]
Objective To study the stability of Triplolide Biological Patches (LTBP). Methods Triplolide content was determinated by HPLC method through strengthen test, accelerated test, and long-term restained sample testing. And the stability of LTBP was investigated. Results Triptolide was relatively stable due to light, temperature, humidity, accelerated testing, and long-term testing. Conclusion The results show that LTBP could be relatively stable in the commercial packaging and storage condition in market.
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[基金项目]
福建省科技重大专项(2009YZ0001-1-3);福建省医学创新项目(2009-CX-16);福建省省属公益类科研院所基本科研专项(2011R1034-3)