[关键词]
[摘要]
目的 优化三拗汤滴丸的制备工艺。方法 以滴丸的成型、圆整度、滴距、滴速、基质与药物比为主要考察因素,对三拗汤滴丸的制备进行优化。结果 最佳工艺条件为药物与基质比为1∶3,滴距为4 cm,温度75 ℃。结论 此方法制备工艺简单、操作方便,制得的滴丸丸重差异小、综合质量好,符合滴丸的质量要求,可以用于三拗汤滴丸的制备。
[Key word]
[Abstract]
Objective To optimize the formation technology for Sanaotang Dropping Pills (SDP). Methods To choose the molding, roundness, dropping distance, dropping speed, and ratio of the matrix to the drugs as main factors, the best method to make SDP was optimized. Results The optimum technology condition was as follows: The ratio of matrix to drugs was 1:3, the dropping distance was 4 cm, and the temperature was 75 ℃. Conclusion The method is simple and covenient, and SDP with low pill weight variation and good quality could be produced under the conditions.
[中图分类号]
[基金项目]
国家科技支撑计划资助项目(2006BAI06A01-02)