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[摘要]
罗替戈汀为选择性多巴胺D1/D2/D3受体激动剂,其透皮贴剂是第一个非麦角类多巴胺受体激动剂贴剂。罗替戈汀贴剂24 h有效,能对帕金森病人持续提供多巴胺能刺激,目前获得FDA和EMA批准上市。对罗替戈汀贴剂研究情况进行简要综述。
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[Abstract]
Rotigotine transdermal patch is the first transdermal non-ergot dopamine agonist, which is a selective dopamine D1/D2/D3 receptor agonist. Rotigotine patch is effective over 24 h providing a continuous dopaminergic stimulation in patients with Parkinson’s disease (PD) and is approved for use in treatment of PD by the FDA and EMA. This paper is a review of current status of Rotigotine transdermal patch.
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