[关键词]
[摘要]
贴剂的溶出度测定可用于指导贴剂的研究,提高贴剂的研制水平。贴剂的溶出度与其他固体制剂溶出度测定没有多大差别,一般的溶出度测定方法均可用于贴剂的溶出度测定。通过比较固体制剂溶出度的研究方法,阐述贴剂溶出度测定的方法、溶出溶剂的选择、溶出度的检测方法、溶出数据的处理等,介绍新型制剂透皮贴剂的溶出度研究情况,为贴剂的进一步研究提供参考。
[Key word]
[Abstract]
The determination of dissolution rate could be used to guide emplastrum research and elevates the research levels. There is little difference of dissolution rate between emplastrum and other solid preparations’, so the ordinary method for dissolution rate determination could be used for emplastrum. Research methods for dissolution rate of solid preparation and emplastrum are compared and determination method, solvent selection, test methods, and data processing of dissolution rate are explained. The dissolution rate of new type transdermal emplastrm is introduced so as to provide the reference for the further research on transdermal emplastrum.
[中图分类号]
[基金项目]
福建省科技重大专项(2009YZ0001-1-3);福建省医学创新项目(2009-CX-16)