[关键词]
[摘要]
毒性病理同行评议(peer review)的目的是核实病理诊断和病理解释的正确性,提高病理报告的质量,执行的时机通常在试验总报告完成前。负责同行评议的病理学家将复查足够的切片和病理数据,帮助试验病理学家进一步确认、精炼病理诊断和数据解释。同行评议需筛选复查的材料由试验病理学家提供,必要时,可临时成立病理专家小组来解决争议或分歧。试验病理学家根据同行评议讨论产生的结果对病理数据和病理报告进行相应修改,并签署最终病理报告,是唯一对试验最终病理数据和病理报告内容负责的人。同行评议病理学家需出具签名的同行评议报告,报告中描述同行评议的程序,确认试验病理学家的病理报告是正确、恰如其分地反应病理数据。试验的病理学家也需要在同行评议报告上签名,以表明同意同行评议病理学家的观点。总结了毒性病理同行评议当前执行的类型和模式推荐,可根据特定试验需要而进行改变。
[Key word]
[Abstract]
The aim of peer review on toxicological pathology is to verify and improve the accuracy and quality of pathology diagnoses and data interpretations. The peer review on toxicological pathology is commonly performed before a study report completed. The peer review pathologist will review enough biopsys and pathological data to assist the study pathologist in refining pathology diagnoses and data interpretations. Data supplied by the study pathologist are to be reviewed and selected by the peer review pathologist. The consultations with the additional experts or a pathological panel may be used to resolve discrepancies if necessary. The study pathologist is solely responsible for the content of the final pathological data and reports, modifies the results according to the peer review discussions, and signs the final pathologist’s report. The peer review pathologist should give a signed peer review report with describing the peer review process and confirming that the study pathologist’s report could accurately and appropriately reflect the pathology data. The study pathologist also needs to check back and sign his or her name on the peer review report, which is proved to agree with the peer review pathologist. The types and modes currently implemented by the peer review on toxicological pathology should be recommended and may be modified to meet the demand of a specific study.
[中图分类号]
[基金项目]