华蟾素注射液是我国自行研制开发的二类新药，是由中华大蟾蜍Bufo bufo gargarizans皮提取的主要成分经加工制成的水溶性制剂，具有良好的抗肿瘤作用，是我国临床中应用较广的抗肿瘤药物，尤其对肝癌的效果较好。其不仅对多种肝癌细胞有杀伤和抑制作用，而且许多临床医生发现华蟾素单用及联合介入治疗等手段治疗肝癌均收到良好的效果。对华蟾素抗肝癌的基础和临床最新研究进行综述，为进一步开发和应用提供参考。

Cinobufacini Injection is the second class new drug independently developed by China, which is water-soluble preparations processed by the main component of Bufo bufo gargarizans skin. As a kind of Chinese materia medica with antitumor effect, Cinobufagin Injection is widely used in clinical practice, especially in anti-liver cancer. It could not only inhibit and kill various kinds of hepatoma carcinoma cells, but also be satisfactory effective in treating patients with liver cancer either when applied lonely or together with interventional therapy. This paper will rewiew the latest progress on the basic and clinical application in treating liver cancer of Cinobufagin Injection..