[关键词]
[摘要]
综述石杉碱甲的研究进展,分别从作用机制、药理作用、合成以及结构修饰等方面对石杉碱甲的研究进行总结,并简述其发展方向:ZT-1作为石杉碱甲的替代物,已经在欧洲完成Ⅱ期临床,有望成为我国具有自主知识产权,又有希望打入国际市场的创新药物。
[Key word]
[Abstract]
The research and development of huperzine A are summarized separately by its mechanism, pharmacology, synthesis, and the structure modification and its development direction is outlined in this paper. ZT-1 as a substitute of huperzine A, the Phase II trial in clinic has been completed in Europe. Huperzine A as an innovation drug is expected to enter the international market with the Chinese intellectual property.
[中图分类号]
[基金项目]