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目的:研究北鹤虱(天名精的果实)的化学成分。方法:通过各种色谱手段(silica gel、ODS、HPLC)对北鹤虱甲醇提取物的二氯甲烷层进行分离纯化,通过1H-NMR、13C-NMR等波谱技术确定化合物的结构。结果:分离并鉴定了5个倍半萜类化合物,分别为特勒内酯(1)、3-epiisotelekin(2)、11β,13-dihydro-1-epi-inuviscolide(3)、天名精内酯酮(4)、天名精内酯醇(5)。结论:化合物2、3为首次从天名精属植物分离得到。
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[Abstract]
Objective: To investigate the chemical constituents from Carpesii Fructus (the dry fruits of Carpesium abrotanoides). Methods: The compounds were isolated by chromatography (silica gel, ODS, and HPLC)and identified on the basis of physico-chemical constants and spectral analysis (1H-NMR and 13C-NMR). Results: Five sesquiterpenoids were isolated and their structures were identified as telekin (1), 3-epi-isotelekin (2), 11β, 13-dihydro-1-epi-inuviscolide (3), carabrone (4), and carabrol (5). Conclusion: Compounds 2 and 3 are isolated from the plants of Carpesium L. for the first time.
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