[关键词]
[摘要]
电离辐射超过一定剂量时,可使几乎所有器官、系统均发生病理改变。电离辐射后产生的大量炎性因子和趋化因子也会参与皮肤、肺和大脑的反应,导致放射性皮炎、放射性肺、脑损伤等。因此需要开发能够有针对性的防治电离辐射的药物。抗电离辐射药物包括恢复造血功能药物、抗氧化剂、抗炎药和天然抗辐射药。总结了抗电离辐射药物的研究进展,希望为抗电离辐射药物的选择和研发提供参考。
[Key word]
[Abstract]
When ionizing radiation exceeds a certain dose, it can cause pathological changes in almost all organs and systems. The large amount of inflammatory and chemokines produced after ionizing radiation can also participate in the reactions of the skin, lungs, and brain, leading to radiation dermatitis, radiation lung, brain damage, and so on. Therefore, it is necessary to develop targeted drugs for the prevention and treatment of ionizing radiation. Anti-ionizing radiation drugs include drugs for restoring hematopoietic function, antioxidants, anti-inflammatory drugs, and natural anti-radiation drugs. This article summarizes the research progress of anti-ionizing radiation drugs, hoping to provide reference for the selection and development of anti-ionizing radiation drugs.
[中图分类号]
R979.61
[基金项目]