目的 研究玉屏风滴丸联合丙酸氟替卡松吸入气雾剂治疗支气管哮喘的临床疗效。方法 选取2016年4月—2018年4月中国人民解放军联勤保障部队第九八八医院收治的240例支气管哮喘患者为研究对象，将所有患者随机分为对照组和治疗组，每组各120例。对照组患者吸入丙酸氟替卡松吸入气雾剂，2揿/次，2次/d；治疗组患者在对照组治疗的基础上口服玉屏风滴丸，1袋/次，3次/d。两组患者持续治疗14 d。观察两组的临床疗效，比较两组的临床症状缓解时间、肺功能指标、血清细胞因子水平。结果 治疗后，对照组和治疗组的总有效率分别为78.33%、95.00%，两组比较差异具有统计学意义（P<0.05）。治疗后，治疗组咳嗽消失时间、肺部啰音消失时间、发热消退时间均短于对照组患者，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者一秒用力呼气容积（FEV1）、呼气高峰流量（PEFR）和FEV1/用力肺活量（FVC）均显著升高，同组治疗前后比较差异有统计学意义（P<0.05）；并且治疗组FEV1、PEFR和FEV1/FVC显著高于对照组，两组比较差异有统计学意义（P<0.05）。治疗后，两组患者肿瘤坏死因子-α（TNF-α）、超敏C反应蛋白（hs-CRP）和白细胞介素-6（IL-6）平均显著降低，同组治疗前后比较差异有统计学意义（P<0.05）；并且治疗组TNF-α、hs-CRP和IL-6水平显著低于对照组（P<0.05）。结论 玉屏风滴丸联合丙酸氟替卡松吸入气雾剂治疗支气管哮喘具有较好的临床疗效，能够缓解患者临床症状，改善肺功能指标，降低血清炎性因子水平，安全性较高，具有一定的临床推广应用价值。

Objective To study the clinical effect of Yupingfeng Dropping Pills combined with Fluticasone Propionate Inhaled Aerosol in treatment of bronchial asthma. Methods Patients (200 cases) with bronchial asthma in the 988th Hospital of PLA Joint Logistics Support Force from April 2016 to April 2018 were randomly divided into control and treatment groups, and each group had 120 cases. Patients in the control group were inhalation administered with Fluticasone Propionate Inhaled Aerosol, 2 press/time, twice daily. Patients in the treatment group were po administered with Yupingfeng Dropping Pills on the basis of the control group, 1 bag/time, three times daily. Patients in two groups were treated for 14 d. After treatment, the clinical efficacies were evaluated, and the remission time of clinical symptoms, and lung function and serum cytokine levels in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 78.33% and 95.00%, respectively, and there was difference between two groups (P<0.05). After treatment, cough disappearance time, lung rale disappearance time, and fever subsidence time in the treatment group were shorter than those in the control group, and there was difference between two groups (P<0.05). After treatment, FEV1, PEFR, and FEV1/FVC in two groups were significantly increased, and the difference was statistically significant in the same group (P<0.05). And the lung function indexes in the treatment group were significantly higher than those in the control group, with significant difference between two groups (P<0.05). After treatment, the levels of TNF-α, hs-CRP, and IL-6 in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the serum cytokine levels in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P< 0.05). Conclusion Yupingfeng Dropping Pills combined with Fluticasone Propionate Inhaled Aerosol has clinical curative effect in treatment of bronchial asthma, can alleviate clinical symptoms, improve lung function, and reduce the level of serum inflammatory factors, with good safety, which has a certain clinical application value.