目的 探讨脑心通胶囊联合依达拉奉注射液与阿司匹林肠溶片治疗心源性脑梗死的临床疗效。方法 选取2017年12月—2018年12月西南医科大学附属医院接诊的60例心源性脑梗死患者作为研究对象，按数字表法随机将患者分为对照组和治疗组，每组各30例。对照组患者口服阿司匹林肠溶片，150 mg/次，1次/d，同时口服脑心通胶囊，3粒/次，3次/d。治疗组静脉滴注依达拉奉注射液，30 mg加入0.9%氯化钠注射液100 mL中，2次/d，同时口服脑心通胶囊，3粒/次，3次/d。两组均连续治疗14 d。观察两组患者的临床疗效，比较两组治疗前后的神经功能损伤情况和血流动力学指标。结果 治疗后，对照组和治疗组的总有效率分别为76.67%、86.67%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组神经功能缺损评分表（NHSS）评分显著降低，日常生活活动能力（ADL）显著升高（P<0.05）；治疗后，治疗组神经功能损伤评分显著优于对照组（P<0.05）。治疗后，两组全血高切黏度、全血低切黏度、血细胞比容、纤维蛋白原水平均显著降低（P<0.05）；治疗后，治疗组血流动力学指标显著低于对照组（P<0.05）。结论 脑心通胶囊联合依达拉奉注射液治疗心源性脑梗死具有较好的临床疗效，可促进神经功能恢复，改善血流动力学指标，具有一定的临床推广应用价值。

Objective To investigate the clinical effect of Naoxintong Capsules combined with Edaravone Injection and Aspirin Enteric-coated Tablets in treatment of cardiogenic cerebral infarction. Methods Patients (60 cases) with cardiogenic cerebral infarction in The Affiliated Hospital of Southwest Medical University from December 2017 to December 2018 were randomly divided into control and treatment groups, and each group had 30 cases. Patients in the control group were po administered with Aspirin Enteric-coated Tablets, 150 mg/time, once daily, and were po administered with Naoxintong Capsules, 3 grains/time, three times daily. Patients in the treatment group were iv administered with Edaravone Injection, 30 mg added into 0.9% Sodium Chloride Injection 100 mL, twice daily, and were po administered with Naoxintong Capsules, 3 grains/time, three times daily. Patients in two groups were treated for 14 d. After treatment, the clinical efficacy was evaluated, and neurological impairment and the hemodynamics indexes in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups was 76.67% and 86.67% (P < 0.05). After treatment, the NHSS scores in two groups was significantly decreased, but ADL scores was increased (P< 0.05). After treatment, these scores in the treatment group were significantly better than those in the control group (P < 0.05). After treatment, the whole blood high shear viscosity, whole blood low shear viscosity, hematocrit, and fibrinogen levels in two groups were significantly decreased (P< 0.05). After treatment, hemodynamics indexes in the treatment group were significantly lower than those in the control group (P < 0.05). Conclusion Naoxintong Capsules combined with Edaravone Injection in treatment of cardiogenic cerebral infarction has a good clinical effect, can promote the recovery of nerve function, and improve hemodynamic indexes, which has a certain clinical application value.