目的 调查分析福州总医院住院患者分剂量使用抗癫痫片剂的使用情况和存在的问题，为保障患者用药安全提供参考。方法 随机抽取福州总医院2017年6~12月口服抗癫痫药物片剂的217名患者出院病历进行回顾性分析，统计分析不同抗癫痫药物分剂量使用情况及使用分剂量抗癫痫药物患者年龄、使用科室、不同癫痫药物分至不同剂量的情况。结果 分剂量使用抗癫痫片剂使用率为30.73%，分剂量使用率最高的药物为苯巴比妥，分剂量使用最高的科室为新生儿病区，丙戊酸钠缓释片分剂量的使用最多，均分至1/2片。结论 福州总医院抗癫痫药片剂分剂量的使用基本合理，药师应对片剂分剂量的准确性与合理性进行全程的药学监督，促进患者安全合理用药。

Objective To analyze the situation of oral antiepileptic drugs splitting tablets in Fuzhou General Hospital, and to make sure medication safety for the hospitalized patients. Methods Prescriptions (217pieces) including oral antiepileptic drugs tablets were analyzed from June 2017 to December 2017 in Fuzhou General Hospital, and the different doses of antiepileptic drugs and the use of different doses of antiepileptic drugs in patients with age, use of departments, different epileptic drugs to different doses of the situation were analyzed statistically. Results The usage rate of oral antiepileptic drugs splitting tablets was 30.73%. The drug with highest dose was phenobarbital. The department with highest dose was the neonatal ward. The splitting using of Sodium Valproate Sustained Release Tablets was the most, and all were splitted into 1/2 tablets. Conclusion The use of oral antiepileptic drugs splitting tablets in Fuzhou General Hospital is basically reasonable. Pharmacists should divide the pieces accurately to reduce the fragmentation defects and promote safe.