目的 探讨卵磷脂络合碘胶囊联合康柏西普眼用注射液治疗视网膜中央静脉阻塞的临床疗效。方法 选取2016年10月-2018年10月在甘孜藏族自治州人民医院接受治疗的100例视网膜中央静脉阻塞患者作为研究对象，随机将所有患者分为对照组和治疗组，每组各50例。对照组患者给予康柏西普眼用注射液，每个月玻璃体腔内每次给药0.5 mg/眼。治疗组在对照组基础上口服卵磷脂络合碘胶囊，3粒/次，3次/d。两组患者持续治疗3个月。观察两组患者的临床疗效，比较治疗前后两组患者的眼压（IOP）、最佳矫正视力（BCVA）、黄斑中心凹视网膜厚度（CRT）、血管内皮生长因子（VEGF）、一氧化氮（NO）和内皮素-1（ET-1）水平。结果 治疗后，对照组和治疗组的总有效率分别为82.00%、96.00%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者的IOP、BCVA和CRT水平显著降低，同组治疗前后比较差异具有统计学意义（P<0.05）；且治疗组治疗后的上述指标水平均明显低于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者VEGF和ET-1水平显著降低，NO水平显著升高，同组治疗前后比较差异具有统计学意义（P<0.05）；且治疗后治疗组VEGF、ET-1和NO水平显著优于对照组，两组比较差异具有统计学意义（P<0.05）。结论 卵磷脂络合碘胶囊联合康柏西普眼用注射液治疗视网膜中央静脉阻塞能够显著提高患者视力，改善机体细胞因子水平，具有一定的临床推广应用价值。

Objective To investigate the clinical efficacy of Iodized Lecithin Capsules combined with Conbercept Ophthalmic Injection in treatment of central retinal vein occlusion. Methods Patients (100 cases) with central retinal vein occlusion in Ganzi Tibetan Autonomous Prefecture People's Hospital from October 2016 to October 2018 were randomly divided into control and treatment groups, and each group had 50 cases. Patients in the control group were given Conbercept Ophthalmic Injection, 0.5 mg/eye in vitreous cavity every month. Patients in the treatment group were po administered with Iodized Lecithin Capsules on the basis of the control group, 3 grains/time, three times daily. Patients in two groups were treated for 3 month. After treatment, the clinical efficacy was evaluated, and the levels of IOP, BCVA, CRT, VEGF, NO, and ET-1in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment group were 82.00% and 96.00%, respectively, and there were differences between two groups (P < 0.05). After treatment, the levels of IOP, BCVA, and CRT in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). And the indexes in the treatment group after treatment were significantly lower than those in the control group, with significant difference between two groups (P < 0.05). After treatment, VEGF and ET-1 levels in two groups were significantly decreased, but NO levels in two groups were significantly increased, and the difference was statistically significant in the same group (P < 0.05). And the VEGF, ET-1 and NO levels in the treatment group were significantly better than those in the control group, with significant difference between two groups (P < 0.05). Conclusion Iodized Lecithin Capsules combined with Conbercept Ophthalmic Injection can significantly improve the vision of patients, and improve the level of cytokines in the body, which has a certain clinical application value.