目的 分析首都医科大学附属北京佑安医院2015— 2017年保肝药物的使用情况，为保肝药物的合理使用和干预提供参考。方法 回顾性分析首都医科大学附属北京佑安医院2015— 2017年保肝药物的销售金额，并计算用药频度（DDDs）、限定日费用（DDC）和排序比（B/A）等，分析保肝药物的临床应用情况。结果 保肝药物的销售金额占全院总药品销售金额的18%左右。新医改后，保肝药物年销售额下降了19.85%。双环醇片和扶正化瘀胶囊的DDDs连续3年排名前3名，注射用丁二磺酸腺苷蛋氨酸和异甘草酸镁注射液的DDC连续3年位居前3位。结论 首都医科大学附属北京佑安医院保肝药物的使用基本合理，希望临床选择药物时在保证安全、有效的基础上，提高对药物的经济性的重视，来实现降低药品费用，进而控制医疗成本的目的。

Objective To analyze the use of hepatoprotective drugs in Beijing You'an Hospital, Capital Medical University from 2015 to 2017, so as to provide references for the rational use and intervention of these drugs. Methods The application data of hepatoprotective drugs in Beijing You'an Hospital, Capital Medical University from 2015 to 2017 were statistically analyzed in terms of total sale amount, defined daily dose system (DDDs), daily drug cost (DDC), the ranking ratio (B/A), and so on. Results The sale amount of hepatoprotective drugs accounted for about 18% of the total sales volume of the hospital. The sale amount of hepatoprotective drugs fell by 19.85% after the new medical reform. DDDs of Bicyclol Tablets and Fuzheng Huayu Capsules were located in the top three for three years. DDC of Ademetionine 1,4-Butanedisulfonate for injection and Magnesium Isoglycyrrhizinate Injection were located in the top three for three years.Conclusion The application of hepatoprotective drugs in Beijing You'an Hospital, Capital Medical University is relatively reasonable. In order to control the cost of medical care, clinicians should attach importance to the economy of drugs on the basis of the safety and effectiveness of drugs.