目的 探讨丹黄祛瘀胶囊联合左氧氟沙星片治疗慢性盆腔炎的临床疗效。方法 选取2016年12月—2018年3月郑州大学第五附属医院收治的94例慢性盆腔炎患者作为研究对象，按照随机数字表法将患者分为对照组和治疗组，每组各47例。对照组患者口服左氧氟沙星片，0.5 g/次，1次/d。治疗组在对照组治疗的基础上口服丹黄祛瘀胶囊，3粒/次，3次/d。两组均连续治疗14 d。观察两组患者的临床疗效，比较两组患者的临床症状消失时间和血清炎症因子水平。结果 治疗后，治疗组的总有效率为93.62%，显著高于对照组的78.72%，两组比较差异具有统计学意义（P<0.05）。治疗后，治疗组下腹疼痛、腰骶胀痛、带下异常消失时间均短于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者的C反应蛋白（CRP）、白细胞介素-1β（IL-1β）、白细胞介素-6（IL-6）、肿瘤坏死因子α（TNF-α）水平均显著降低，同组治疗前后比较差异具有统计学意义（P<0.05）；治疗后，治疗组的CRP、IL-1β、IL-6、TNF-α水平均显著低于对照组，两组比较差异具有统计学意义（P<0.05）。结论 丹黄祛瘀胶囊联合左氧氟沙星片治疗慢性盆腔炎的疗效确切，能显著改善患者的临床症状，降低炎症因子水平，具有一定的临床推广应用价值。

Objective To explore the clinical efficacy of Danhuang Quyu Capsules combined with Levofloxacin Tablets in treatment of chronic pelvic inflammatory disease. Methods Patients (94 cases) with chronic pelvic inflammatory disease in the Fifth Affiliated Hospital of Zhengzhou University from December 2016 to March 2018 were randomly divided into control and treatment groups, and each group had 47 cases. Patients in the control group were po administered with Levofloxacin Tablets, 0.5 g/time, once daily. Patients in the treatment group were po administered with Danhuang Quyu Capsules on the basis of the control group, 3 grains/time, three times daily. Patients in two groups were treated for 14 d. After treatment, the clinical efficacy was evaluated, and the disappearance time of clinical symptoms, and the serum inflammatory factor levels in two groups were compared. Results After treatment, the clinical efficacy in the treatment group was 93.62%, which was significantly higher than 78.72% in the control group, and there were differences between two groups (P<0.05). After treatment, the disappearance time of lower abdominal pain, lumbosacral pain, and abnormal leukorrhea in the treatment group were significantly shorter than those in the control group, with significant difference between two groups (P<0.05). After treatment, levels of CRP, IL-1β, IL-6, and TNF-α were significantly decreased in two groups, and there were differences in the same group (P < 0.05). After treatment, levels of CRP, IL-1β, IL-6, and TNF-α in the treatment group were lower than those in the control group, and there were differences between two groups (P<0.05). Conclusion Danhuang Quyu Capsules combined with Levofloxacin Tablets has significant clinical effect in treatment of chronic pelvic inflammatory disease, can significantly improve the clinical symptoms of patients, and reduce the levels of inflammatory factors, which has a certain clinical application value.