近年来，丙戊酸有关的治疗药物监测研究报道较多。在临床实践中治疗药物监测作为丙戊酸剂型选择和治疗方案调整的参考依据，可以提高丙戊酸临床疗效、减少药物不良反应，考察患者的服药依从性。丙戊酸在临床使用时进行治疗药物监测对丙戊酸的临床个体化、合理用药有着重要的指导意义。

In recent years, therapeutic drug monitoring on valproic acid has been widely reported. As a reference for valproic acid dosage form selection and treatment program adjustment, therapeutic drug monitoring can improve the clinical efficacy of valproic acid, reduce adverse drug reactions, and investigate the compliance of patients in clinical practice. Therapeutic drug monitoring on valproic acid has important guiding significance for clinical individualization and rational use of valproic acid.

2016-2017年度安徽医科大学校科研基金项目（2017xkj063）；北京医学奖励基金会资助项目（YJHYXKYJJ-414）