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[摘要]
目的 评价2014-2017年天津市南开区中医医院糖尿病治疗药物的使用情况。方法 对2014-2017年天津市南开区中医医院药物的用量、销售金额、用药频度(DDDs)、日均药费(DDC)及药品排序比(B/A)等进行统计和分析。结果 2014-2017年,糖尿病治疗药物的用药总金额呈下降趋势,其中胰岛素及其类似物的占比最高,约占32%以上,非磺酰脲类胰岛素促泌剂类药物与α-糖苷酶抑制剂类药物分列2、3位。前10位的口服糖尿病治疗药物中,阿卡波糖片的用药金额始终处于首位; 2014-2017年,盐酸二甲双胍片的DDDs一直处于第1位,盐酸吡格列酮片的用药金额及DDDs均呈较为明显的上升趋势。前10位的口服糖尿病治疗药物DDC基本稳定。盐酸二甲双胍片的B/A值最大,格列美脲片、罗格列酮钠片、盐酸吡格列酮片的B/A均接近1.00。结论 天津市南开区中医医院糖尿病治疗药物的应用总体上合理,但仍需加强监督管理。
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[Abstract]
Objective To investigate the utilization of antidiabetic agents in Tianjin Nankai Hospital of TCM from 2014 to 2017. Methods The utilization information of antidiabetic agents in Nankai Hospital of TCM from 2014 to 2017 was extracted, and the consumption sum, defined daily doses (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) were analyzed statistically. Results From 2014 to 2017, the total consumption sums of antidiabetic agents showed a trend of decrease. The composing ratio of consumption sum of insulin and insulin similitude was the highest, accounting for 32%. Consumption sums of non sulfonylurea insulin secreting agent and α-glucosidase inhibitor were ranked the second and third, respectively. In the top 10 oral antidiabetic drugs, consumption sum of Acarbose Tablets were always in the first place. DDDs of Metformin Hydrochloride Tablets remained the first place from 2014 to 2017. Consumption sum and DDDs of Pioglitazone Hydrochloride Tablets had shown an obvious increase. DDC of the top 10 oral antidiabetic drugs were stable. B/A of Metformin Hydrochloride Tablets was the highest. B/A of Glimepiride Tablets, Rosiglitazone Sodium Tablets, and Pioglitazone Hydrochloride Tablets were closed to 1.00. Conclusion The utilization of antidiabetic agents in Tianjin Nankai Hospital of TCM is rational on the whole, meanwhile. Supervision should be strengthened to standardize medication behavior.
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