目的 探讨盘龙七片联合塞来昔布胶囊治疗类风湿性关节炎的临床疗效。方法 选取2014年3月-2016年3月在咸阳市中心医院就诊的86例类风湿性关节炎患者作为研究对象，所有患者随机、双盲、对照分为对照组和治疗组，每组各43例。对照组患者口服塞来昔布胶囊，100 mg/次，2次/d；治疗组在对照组治疗的基础上口服盘龙七片，4片/次，3次/d。两组患者均连续治疗3个月。观察两组的临床疗效，同时比较治疗前后两组的视觉模拟评分（VAS）、DAS28评分和血清学指标。结果 治疗后，对照组和治疗组的总有效率分别为79.07%、95.35%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者的VAS评分和DAS28评分均显著降低，同组治疗前后比较差异具有统计学意义（P<0.05）；治疗后，治疗组患者各评分均显著低于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者的C反应蛋白（CRP）、白细胞介素-6（IL-6）以及类风湿因子水平均显著降低，同组治疗前后比较差异具有统计学意义（P<0.05）；治疗后，治疗组患者血清学指标显著低于对照组，两组比较差异具有统计学意义（P<0.05）。结论 盘龙七片联合塞来昔布胶囊治疗类风湿性关节炎疗效显著，能够减轻患者关节疼痛，降低血清学指标，安全性高，具有一定的临床推广应用价值。

Objective To investigate the clinical efficacy of Panlongqi Tablets combined with Celecoxib Capsules in treatment of rheumatoid arthritis. Methods Patients (86 cases) with rheumatoid arthritis in Xianyang Central Hospital from March 2014 to March 2016 were divided into control and treatment groups according to randomization, double-blind and control method, and each group had 43 cases. Patients in the control group were po administered with Celecoxib Capsules, 100 mg/time, twice daily. Patients in the treatment group were po administered with Panlongqi Tablets on the basis of the control group, 4 tablets/time, three times daily. Patients in two groups were treated for 3 months. After treatment, the clinical efficacy was evaluated, and the VAS scores, DAS28 scores, and serological indicators in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups was 79.07% and 95.35%, respectively, and there were differences between two groups (P<0.05). After treatment, the VAS scores and DAS28 scores in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). After treatment, the scores in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). After treatment, the CRP, IL-6, and rheumatoid factor levels in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). After treatment, the serological indicators in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Panlongqi Tablets combined with Celecoxib Capsules has significant effect in treatment rheumatoid arthritis, can alleviate the joint pain, reduce the serological indicators, with good safety, which has a certain clinical application value.