目的 探讨治糜康栓联合阿奇霉素分散片治疗慢性宫颈炎的临床疗效。方法 选取2016年8月-2017年8月在西安市高陵区医院接受治疗的168例慢性宫颈炎患者，随机分为对照组和治疗组，每组各84例。对照组口服阿奇霉素分散片，0.5 g/次，1次/d；治疗组在对照组治疗的基础上给予治糜康栓，于睡前清洗外阴部，将其推入阴道深部，1粒/次，1次/2 d。两组患者均连续治疗10 d。观察两组的临床疗效，比较两组宫颈修复时间、阴道排液时间、血清炎性因子、免疫球蛋白水平。结果 治疗后，两组总有效率分别为85.71%、96.43%，两组比较差异有统计学意义（P<0.05）。治疗后，治疗组宫颈修复时间、阴道排液时间均明显短于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组血清IL-4、TNF-α和PGE₂水平均显著降低，同组治疗前后比较差异有统计学意义（P<0.05）；且治疗组血清炎性因子明显低于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组血清IgA、IgG、IgM水平显著升高，同组治疗前后比较差异有统计学意义（P<0.05）；且治疗组免疫球蛋白明显高于对照组，两组比较差异具有统计学意义（P<0.05）。结论 治糜康栓联合阿奇霉素分散片治疗慢性宫颈炎具有较好的临床疗效，可改善临床症状，减轻炎症反应，提高免疫功能，具有一定的临床推广应用价值。

Objective To investigate the clinical efficacy of Zhimikang Suppository combined with Azithromycin Dispersible Tablets in treatment of chronic cervicitis. Methods Patients (168 cases) with chronic cervicitis in Gaoling District Hospital of Xi'an from August 2016 to August 2017 were randomly divided into control and treatment groups, and each group had 84 cases. Patients in the control group were po administered with Azithromycin Dispersible Tablets, 0.5 g/time, once daily. Patients in the treatment group were given Zhimikang Suppository on the basis of the control group, pushed into the deep part of the vagina after cleaning the vulva before bedtime, 1 grain/time, once every other day. Patients in two groups were treated for 10 d. After treatment, the clinical efficacies were evaluated, and cervical repair time, vaginal drainage time, serum inflammatory factor, and immunoglobulin level in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 85.71% and 96.43%, respectively, and there was difference between two groups (P<0.05). After treatment, cervical repair time and vaginal drainage times in the treatment group were shorter than those in the control group, and there was difference between two groups (P<0.05). After treatment, IL-4, TNF-α, and PGE₂ levels in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And inflammatory factor indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). After treatment, IgA, IgG, and IgM levels in two groups were significantly increased, and the difference was statistically significant in the same group (P<0.05). And immunoglobulin levels in the treatment group were significantly higher than those in the control group, with significant difference between two groups (P<0.05). Conclusion Zhimikang Suppository combined with Azithromycin Dispersible Tablets has clinical curative effect in treatment of chronic cervicitis, can improve clinical symptoms, reduce inflammation, and improve immune function, which has a certain clinical application value.