目的 探讨穿王消炎片联合头孢地尼治疗慢性咽炎的临床疗效。方法 选取2017年7月-2018年4月在许昌市中心医院进行治疗的98例慢性咽炎患者为研究对象，根据住院号的奇偶数将所有患者分为对照组和治疗组，每组各49例。对照组口服头孢地尼片，0.1 g/次，3次/d。治疗组在对照组治疗基础上口服穿王消炎片，0.88 g/次，3次/d。两组均连续治疗2周。观察两组的临床疗效，比较两组临床症状改善时间和炎症因子的变化情况。结果 治疗后，对照组和治疗组的总有效率分别为81.63%、95.92%，两组比较差异具有统计学意义（P<0.05）。治疗后，治疗组咽喉痛痒、咽喉异物感、干咳、分泌物增多等症状改善时间明显短于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组血清C反应蛋白（CRP）、白细胞介素-4（IL-4）、白细胞介素-6（IL-6）、肿瘤坏死因子-α（TNF-α）的表达均较治疗前降低，同组治疗前后比较差异有统计学意义（P<0.05）；治疗后，治疗组CRP、IL-4、IL-6、TNF-α水平显著低于对照组，两组比较差异具有统计学意义（P<0.05）。结论 穿王消炎片联合头孢地尼治疗慢性咽炎具有较好的临床疗效，可显著改善患者临症状，降低机体炎症因子水平，具有一定的临床推广应用价值。

Objective To investigate the clinical efficacy of Chuanwang Xiaoyan Tablets combined with cefdinir in treatment of chronic pharyngitis. Methods Patients (98 cases) with chronic pharyngitis in Xuchang Central Hospital from July 2017 to April 2018 were divided into treatment group (49 cases) and control group (49 cases) according to the odd and even number of hospitalization. Patients in the control group were po administered with Cefdinir Tablets, 0.1 g/time, three times daily. Patients in the treatment group were po administered with Chuanwang Xiaoyan Tablets on the basis of the control group, 0.88 g/time, three times daily. Patients in two groups were treated for 2 weeks. After treatment, the clinical efficacy was evaluated, and improvement time of clinical symptoms and changes of inflammatory factors in two groups were compared. Results After treatment, the clinical efficacy in the control and treatment group were 81.63% and 95.92%, and there were differences between two groups (P<0.05). After treatment, the improvement time of symptoms such as sore throat, laryngopharyngeal foreign body sensation, dry cough and increased secretion in the treatment group was significantly shorter than those in the control group, and there were differences between two groups (P<0.05). After treatment, CRP, IL-4, IL-6, and TNF-α were significantly decreased in two groups, and there were differences in the same group (P<0.05). After treatment, CRP, IL-4, IL-6, and TNF-α in the treatment group were lower than those in the control group, and there were differences between two groups (P<0.05). Conclusion Chuanwang Xiaoyan Tablets combined with cefdinir has significant clinical effect in treatment of chronic pharyngitis, and can significantly improve the clinical symptoms and reduce the inflammatory factors, which has a certain clinical application value.