目的 分析注射用丹参（冻干）联合阿托伐他汀钙片治疗伴出血的急性脑梗死的临床疗效。方法 选取2015年1月-2018年1月在青海省心脑血管病专科医院收治的64例伴出血急性脑梗死患者作为研究对象，将所有患者随机分对照组和治疗组，每组各32例。对照组患者口服阿托伐他汀钙片，1片/次，1次/d。治疗组在对照组治疗的基础上静脉滴注注射用丹参（冻干），0.4 g注射用丹参（冻干）加入到100 mL生理盐水中，1次/d。两组患者均连续治疗2周。观察对比两组患者的临床疗效，比较治疗前后两组的NIHSS评分、超敏C反应蛋白（hs-CRP）、血脂水平和再出血情况。结果 治疗后，对照组的总有效率为78.1%，显著低于治疗组的96.9%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者NIHSS评分显著降低，同组治疗前后比较差异具有统计学意义（P<0.05）；治疗后，治疗组NIHSS评分明显低于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，治疗组血清hs-CRP、总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白（LDL-C）水平均显著降低，高密度脂蛋白（HDL-C）水平明显升高，同组治疗前后比较差异具有统计学意义（P<0.05）；治疗后，治疗组hs-CRP和血脂水平显著优于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，对照组再出血率为15.6%，治疗组再出血率为3.1%，两组比较差异具有统计学意义（P<0.05）。结论 注射用丹参（冻干）联合阿托伐他汀钙片治疗伴出血的急性脑梗死具有较好的临床疗效，可提升患者生活质量，改善出血情况，具有一定的临床推广应用价值。

Objective To analyze the clinical efficacy of Danshen (freeze-dried) for injection combined with Atorvastatin Calcium Tablets in treatment of acute cerebral infarction with hemorrhage. Methods Patients (64 cases) with acute cerebral infarction with hemorrhage in Qinghai Cardiovascular and Cerebrovascular Disease Hospital from January 2015 to January 2018 were randomly divided into control and treatment groups, and each group had 32 cases. Patients in the control group were po administered with Atorvastatin Calcium Tablets, 1 tablet/time, once daily. Patients in the treatment group were iv administered with Danshen (freeze-dried) for injection on the basis of the control group, 0.4 g added into normal saline 100 mL, once daily. Patients in two groups were treated for 2 weeks. After treatment, the clinical efficacy was evaluated, and the NIHSS scores, hs-CRP, blood lipids levels, and rebleeding in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control group was 78.1%, which was significantly lower than 96.9% in the treatment group, and there were differences between two groups (P<0.05). After treatment, the NIHSS scores in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). After treatment, the NIHSS scores in the treatment group were significantly lower than those in the control group, and there were differences between two groups (P<0.05). After treatment, hs-CRP, TC, TG, and LDL-C levels in two groups were significantly decreased, but HDL-C levels in two groups were significantly increased, and the difference was statistically significant in the same group (P<0.05). After treatment, hs-CRP and blood lipids levels in the treatment group was significantly better than those in the control group, with significant difference between two groups (P<0.05). After treatment, the rebleeding rate in the control and treatment groups was 15.6% and 3.1%, respectively, and there were differences between two groups (P<0.05). Conclusion Danshen (freeze-dried) for injection combined with Atorvastatin Calcium Tablets has clinical curative effect in treatment of acute cerebral infarction with hemorrhage, can improve the quality of life, and improve bleeding situation, which has a certain clinical application value.