目的 分析南京市第一医院神经内科脑梗死患者使用中药注射剂的不良反应发生规律及特点，为中药注射剂的合理使用提供参考依据。方法 采用回顾性分析方法，筛选符合要求的不良反应报告，记录相关信息，结合指南和文献进行分析。结果 符合要求的报告有204份，不良反应发生特点为涉及药品共有12种，分为3大类，其中活血化瘀类占比最大（85.5%）；有51.5%存在药品联用情况；男性居多（61.8%），高峰年龄段为60~70岁（25.0%）；不良反应多在用药第1天（72.1%）出现；皮肤及其附件损害最多（29.6%），其次为神经系统损害（23.5%）和心血管系统损害（13.6%）。结论 应加强中药注射剂不良反应监测工作，促进临床安全用药。

Objective To analyze the laws and characteristics of the Adverse Drug Reaction (ADR) of traditional Chinese medicine injection in treatment of cerebral infarction in Nanjing First Hospital, and to provide a reference for rational drug use of traditional Chinese medicine injection. Methods A retrospective study was conducted on the ADR reports. The related information was recorded. Then the data according to related guidelines and documents were analyzed. Results A total of 204 ADR reports were included according to inclusion criteria. There were 12 kinds of traditional Chinese medicine injections that could be divided into three categories, and the blood-activating and stasis-resolving type made up the largest percentage (85.5%) of the injections. There were 51.5% reports of drug combination use. ADR mostly occurred in the male patients (61.8%) and 60-70 years old (25.0%). 72.1% of ADR appeared after the first time use of medicine. Most of the damage was the skin and accessories (29.6%), followed by nervous system (23.5%) and cardiovascular system (13.6%). Conclusion ADR monitoring of traditional Chinese medicine injection should be strengthened to promote the safety of drug use.