目的 探讨天舒胶囊联合奥扎格雷钠氯化钠注射液治疗脑梗死患者的临床效果。方法 选取2016年4月-2017年4月上海市奉贤区中心医院收治的脑梗死患者150例为研究对象。随机将患者分为对照组和治疗组，每组各75例。对照组静脉滴注奥扎格雷钠氯化钠注射液，250 mL/次，2次/d。治疗组在对照组治疗的基础上口服天舒胶囊，4粒/次，3次/d。两组患者均持续治疗2周。观察两组患者临床疗效，比较两组治疗前后的同型半胱氨酸水平、脑血流图流入容积速度、神经功能缺损评分、日常生活能力评分和不良反应发生情况。结果 治疗后，对照组、治疗组总有效率分别为82.67%、94.67%，两组总有效率比较差异有统计学意义（P<0.05）。治疗后，两组患者同型半胱氨酸水平显著降低，脑血流图流入容积速度均显著升高，同组治疗前后比较差异具有统计学意义（P<0.05）；且治疗后治疗组的同型半胱氨酸水平和脑血流图流入容积速度明显优于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者神经功能缺损评分显著降低，日常生活能力评分显著升高，同组治疗前后比较差异具有统计学意义（P<0.05）；且治疗后治疗组患者的神经功能缺损评分和日常生活能力评分显著优于对照组，两组比较差异具有统计学意义（P<0.05）。治疗期间，治疗组患者不良反应发生率为4.00%，显著低于对照组的14.67%，两组患者比较差异具有统计学意义（P<0.05）。结论 天舒胶囊联合奥扎格雷钠氯化钠注射液治疗脑梗死具有较好的临床疗效，可改善患者的脑部血流状态，促进神经功能恢复，提高生活能力，副反应低，具有一定的临床推广应用价值。

Objective To investigate the clinical effects of Tianshu Capsules combined with Sodium Ozagrel and Sodium Chloride Injection in treatment of cerebral infarction.Methods Patients (150 cases) with cerebral infarction in Shanghai Fengxian District Central Hospital from April 2016 to April 2017 were randomly divided into control and treatment groups, and each group had 75 cases. Patients in the control group were iv administered with Sodium Ozagrel and Sodium Chloride Injection, 250 mL/time, twice daily. Patients in the treatment group were po administered with Tianshu Capsules on the basis of the control group, 4 grains/time, three times daily. Patients in two groups were treated for 2 weeks. After treatment, the clinical efficacy was evaluated, and the homocysteine level, rheoencephalogram inflow volume velocity, neurological deficit score, activity of daily living score, and the adverse reactions in two groups before and after treatment were compared.Results After treatment, the clinical efficacies in the control and treatment groups were 82.67% and 94.67%, respectively, and there was difference between two groups (P < 0.05). After treatment, homocysteine levels in two groups were significantly decreased, but rheoencephalogram inflow volume velocities in two groups were significantly increased, and the difference was statistically significant in the same group (P < 0.05). After treatment, homocysteine levels and rheoencephalogram inflow volume velocities in the treatment group were significantly better than those in the control group, with significant difference between two groups (P < 0.05). After treatment, neurological deficit score in two groups were significantly decreased, but activity of daily living score in two groups were significantly increased, and the difference was statistically significant in the same group (P < 0.05). After treatment, neurological deficit scores and activity of daily living scores in the treatment group were significantly better than those in the control group, with significant difference between two groups (P < 0.05). During the treatment, the incidence of adverse reactions in the treatment group was 4.00%, which was significantly lower than 14.67% in the control group, with significant difference between two groups (P < 0.05). Conclusion Tianshu Capsules combined with Sodium Ozagrel and Sodium Chloride Injection has clinical curative effect in treatment of cerebral infarction, can improve the cerebral blood flow, promote the recovery of neurological function, and improve the living ability, with lower side effects, which has a certain clinical application value.