肺癌的发病率和死亡率居高不下，在治疗过程中面临分子异质性显著、耐药发生普遍、治疗相关不良反应明显等难点。槲皮素可通过抑制细胞增殖、抑制细胞侵袭和转移、抑制血管生成、促进细胞死亡、靶向增强细胞毒性、提高药物敏感性、增强放疗敏感性发挥抗肺癌的作用。总结了槲皮素防治肺癌的药理作用研究进展，为槲皮素的应用提供参考。

The incidence rate and mortality rate of lung cancer remain persistently high, presenting significant challenges during treatment, including notable molecular heterogeneity, widespread drug resistance, and pronounced treatment-related adverse reactions. Quercetin exerts anti-lung cancer effects by inhibiting cell proliferation, suppressing cell invasion and metastasis, inhibiting angiogenesis, promoting cell death, targeting and enhancing cytotoxicity, improving drug sensitivity, and increasing radiotherapy sensitivity. This review summarizes the pharmacological research progress on quercetin in prevention and treatment of lung cancer, providing a reference for its application.

R285.5;R979.1