[关键词]
[摘要]
广藿香醇是一种三环倍半萜类化合物,为广藿香挥发油中主要活性成分。广藿香醇具有抗炎、抗肿瘤、抗菌、抗病毒、抗氧化、免疫调节的药理活性,同时在肺保护、心血管保护、神经保护以及抗糖尿病及其并发症方面表现出独特优势。总结了广藿香醇的药理作用研究进展,旨在为广藿香醇的靶向药物设计和临床转化研究提供科学依据。
[Key word]
[Abstract]
Patchouli alcohol is a tricyclic sesquiterpene compound and the primary active component in Pogostemonis Herba essential oil. The pharmacological activities of patchouli alcohol include anti-inflammatory, anti-tumor, antibacterial, antiviral, antioxidant, and immunomodulatory effects, while also demonstrating unique advantages in lung protection, cardiovascular protection, neuroprotection, and anti-diabetes as well as its complications. This article summarizes the research progress on the pharmacological effects of patchouli alcohol, aiming to provide scientific basis for the targeted drug design and clinical translation research of patchouli alcohol.
[中图分类号]
R285.5
[基金项目]
山东省自然科学基金项目(ZR2022MH181);山东省中医药科技项目(M-2023267);山东省医药卫生科技发展计划项目(202103070897)