心血管疾病包括冠心病（心绞痛、心肌梗死）、心力衰竭、高血压性心脏病、心律失常等，目前位于导致人类死亡病因的首位。黄芩苷可通过减轻心肌炎性损伤、减轻心肌氧化损伤、抑制心肌细胞凋亡、抑制血小板过度激活、抑制心肌纤维化、调节免疫平衡、改善线粒体功能、促进心肌细胞增殖、促进血管新生以减轻心肌损伤和改善心功能，治疗心血管疾病。总结了黄芩苷治疗心血管疾病的药理作用研究进展，为黄芩苷的临床用药提供参考。

Cardiovascular diseases, including coronary heart disease (angina pectoris, myocardial infarction), heart failure, hypertensive heart disease, arrhythmia, etc., are currently the leading causes of human mortality. Baicalin can alleviate myocardial inflammatory injury, reduce myocardial oxidative damage, inhibit myocardial cell apoptosis, inhibit platelet overactivation, inhibit myocardial fibrosis, regulate immune balance, improve mitochondrial function, promote myocardial cell proliferation, promote angiogenesis, and reduce myocardial injury through multiple targets and pathways, thereby improving cardiac function. This article summarizes the pharmacological research progress of baicalin in treatment of cardiovascular diseases, providing reference for the clinical use of baicalin.

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攀枝花市指导性科技计划（2024ZD-S-122）