子宫内膜异位症的发病机制复杂，临床主要的治疗目的为减轻临床症状、限制病灶生长。槲皮素具有多种药理作用，可通过抑制异位细胞增殖、阻止内异细胞侵袭和迁移、减轻氧化应激反应、抑制间质纤维化、抑制新生血管形成、促进异位病灶细胞凋亡、调节下丘脑–垂体–卵巢轴功能治疗子宫内膜异位症。总结了槲皮素治疗子宫内膜异位症的药理作用研究进展，为槲皮素的临床应用提供参考。

The pathogenesis of endometriosis is complex, and the main clinical treatment goal is to alleviate clinical symptoms and limit lesion growth. Quercetin has multiple pharmacological effects, and can treat endometriosis by inhibiting ectopic cell proliferation, preventing invasion and migration of ectopic cells, reducing oxidative stress response, inhibiting interstitial fibrosis, inhibiting angiogenesis, promoting apoptosis of ectopic lesion cells, and regulating hypothalamic-pituitary-ovarian axis function. This article summarizes the pharmacological research progress of quercetin in treatment of endometriosis, providing a reference for the clinical application of quercetin.

R287.4

重庆市科卫联合医学科研项目（2019MSXM007）