皮肤病已成为影响人类生活质量和身心健康的重要疾病，其临床治疗药物存在作用机制单一、停药易复发、个体疗效差异较大、长期不良反应大等缺点。黄芩苷是黄芩中的黄酮类化合物，可通过减轻炎症反应、减轻氧化损伤、抑制角质形成细胞过度增殖、保护皮肤屏障功能、阻止正常皮肤细胞死亡、防治皮肤癌发挥防治多种皮肤病变的作用。总结了黄芩苷治疗皮肤病的药理作用研究进展，为黄芩苷临床应用于皮肤病提供思路。

Skin diseases have become an important disease that affects human quality of life and physical and mental health. Their clinical treatment drugs have disadvantages such as a single mechanism, easy recurrence after discontinuation, significant individual efficacy differences, and large long-term adverse reactions. Baicalin is a flavonoid compound in Scutellariae Radix, which can prevent and treat various skin lesions by reducing inflammation response, alleviating oxidative damage, inhibiting excessive proliferation of keratinocytes, protecting skin barrier function, preventing normal skin cell death, and preventing skin cancer. This article summarizes the pharmacological research progress of baicalin in treatment of skin diseases, providing ideas for the clinical application of baicalin in prevention and treatment of skin diseases.

R285.5;R287.7

四川省科技计划项目（2018JY0654）