多囊卵巢综合征是育龄期女性常见的内分泌疾病，影响女性生殖和健康。黄芪多糖、枸杞多糖、茯苓多糖等中药多糖类化合物可通过调节氧化应激、延缓卵巢纤维化、调节细胞自噬、抑制细胞凋亡、改善胰岛素抵抗、调节糖酵解、调节肠道菌群干预多囊卵巢综合征的发生、发展。综述了中药多糖防治多囊卵巢综合征的药理作用研究进展，以期为进一步的药物研发和临床转化提供参考。

Polycystic ovary syndrome is a common endocrine disorder among women of reproductive age, affecting female reproduction and health. Chinese herbal polysaccharides, such as Astragalus polysaccharides, wolfberry polysaccharides, and Poria polysaccharides, can intervene in the occurrence and progression of polycystic ovary syndrome by modulating oxidative stress, delaying ovarian fibrosis, regulating cell autophagy, inhibiting cell apoptosis, improving insulin resistance, modulating glycolysis, and regulating gut microbiota. This review summarizes the pharmacological research progress of Chinese herbal polysaccharides in prevention and treatment of polycystic ovary syndrome, aiming to provide a reference for further drug development and clinical translation.

R984

国家中医药管理局中医药循证能力提升项目（国中医药科技中药便函[2023]24 号） ； 黑龙江省临床医学研究中心建设项目（LC2020R009）