脓毒症是由感染引发的全身性炎症反应综合征，治疗脓毒症的主要策略包括抗生素、免疫调节药物和血流动力学支持。黄芩苷可通过减轻炎症反应、减轻氧化应激反应、抑制细胞凋亡、改善免疫功能、调节能量代谢水平以控制脓毒症病情发展，减轻心、肝、肺、肾等器官的损伤。总结了黄芩苷防治脓毒症相关器官损伤的药理作用研究进展，为脓毒症的临床治疗提供新策略。

Sepsis is a systemic inflammatory response syndrome caused by infection. The main treatment strategies for sepsis include antibiotics, immunomodulatory drugs, and hemodynamic support. Baicalin can control the progression of sepsis and alleviate damage to organs such as the heart, liver, lungs, and kidneys by reducing inflammation, alleviating oxidative stress, inhibiting cell apoptosis, improving immune function, and regulating energy metabolism levels. This article summarizes the pharmacological research progress of baicalin in preventing and treating sepsis related organ damage, providing new strategies for the clinical treatment of sepsis.

R285.5;R978

天津市教委科研计划项目（2022KJ186）