视网膜损伤是多种眼科疾病的共同病理基础，病理机制复杂。川芎嗪可通过减轻炎症反应、减轻氧化应激反应、抑制视网膜细胞凋亡、抑制病理性新生血管形成、改善视网膜血流灌注、阻止视网膜母细胞瘤生长减轻视网膜损伤。总结了川芎嗪防治视网膜损伤的药理作用研究进展，为其在视网膜损伤防治中的应用提供参考。

Retinal injury is a common pathological basis for various ophthalmic diseases, with complex pathological mechanisms. Ligustrazine can alleviate retinal damage by reducing inflammatory responses, mitigating oxidative stress, inhibiting retinal cell apoptosis, suppressing pathological neovascularization, improving retinal blood flow perfusion, and preventing retinoblastoma growth. This article summarizes the pharmacological research progress of ligustrazine in prevention and treatment of retinal damage, providing a reference for its application in retinal injury management.

R285.5;R988.1

云南省科技厅科技计划项目（202401AY070001-294）