近年来我国前列腺癌的发病率明显上升，开发新型治疗药物是当前前列腺癌研究的迫切需求。白藜芦醇是一种天然的多酚类化合物，能够通过抑制细胞增殖、诱导细胞凋亡和自噬、抑制细胞迁移和侵袭、干预表观遗传重编程、靶向线粒体功能抑制前列腺癌的发生、发展。总结了白藜芦醇抗前列腺癌的作用机制研究进展，为白藜芦醇抗前列腺癌的实验和临床研究提供参考。

In recent years, the incidence rate of prostate cancer has increased significantly in China. It is urgent to develop new therapeutic drugs for prostate cancer research. Resveratrol is a natural polyphenolic compound, which can inhibit cell proliferation, induce apoptosis and autophagy, suppress cell migration and invasion, intervene in epigenetic reprogramming, and target mitochondrial function to suppress the occurrence and development of prostate cancer. This article summarizes the research progress on the mechanism of resveratrol in treatment of prostate cancer, providing reference for experimental and clinical studies of resveratrol in treatment of prostate cancer.

R965

湖南省自然科学基金项目（2024JJ9308）；长沙市自然科学基金项目（kq2208112）；湖南省人民医院仁术重点项目（RS2022A13）；湖南省卫生健康高层次人才支持计划资助项目（湘卫函[2023]78号）；湖南师范大学医学部2025年教育教学改革研究项目（32）；湖南师范大学医学部2025年教育教学改革研究项目（63）