[关键词]
[摘要]
抗感染药物在临床治疗感染性疾病中发挥重要作用,但长期或高剂量使用此类药物常伴发药物性肝损伤。不同抗感染药物类型致肝损伤的作用机制各不相同。总结了抗生素、抗病毒药物、抗真菌药物致药物性肝损伤的作用机制研究进展,旨在为患者抗感染药物致药物性肝损伤的诊断、预防和治疗提供参考。
[Key word]
[Abstract]
nti-infective drugs play an important role in the clinical treatment of infectious diseases, but long-term or high-dose use of such drugs is often accompanied by drug-induced liver injury. The mechanism of different types of anti-infective drugs causing liver injury varies. This article summarizes the research progress on mechanism of antibiotics, antiviral drugs, and antifungal drugs in drug-induced liver injury, aiming to provide reference for the diagnosis, prevention, and treatment of drug-induced liver injury in patients with anti-infective drugs.
[中图分类号]
R975
[基金项目]
疫苗接种与重点关注的血液系统疾病发病风险的相关性研究(横20230540)