[关键词]
[摘要]
急性胰腺炎是一种由胰腺自我消化引起的急性炎症性疾病,病情发展迅速、并发症多,治疗难度大。黄芩苷为黄芩根部提取的主要黄酮类化合物,可通过减轻炎症反应、减轻氧化应激反应、纠正微循环障碍、调控细胞凋亡、延缓胰腺纤维化发挥抗急性胰腺炎的作用。总结了黄芩苷防治急性胰腺炎的药理作用研究进展,为急性胰腺炎的临床治疗提供思路。
[Key word]
[Abstract]
Acute pancreatitis is an acute inflammatory disease caused by pancreatic self-digestion, characterized by rapid disease progression, numerous complications, and significant treatment challenges. Baicalin is the primary flavonoid compound extracted from roots of Scutellariae Radix. Baicalin can exert anti-acute pancreatitis effects by reducing inflammation, alleviating oxidative stress, correcting microcirculation disorders, regulating cell apoptosis, and delaying pancreatic fibrosis. This article summarizes the pharmacological research progress of baicalin in prevention and treatment of acute pancreatitis, providing ideas for the clinical treatment of acute pancreatitis.
[中图分类号]
R286.5
[基金项目]
兰州市科技计划项目(2021-1-112)