近年来，我国心血管疾病的患病人数持续攀升，目前临床常用的治疗药物存在部分患者不耐受、长期用药不良反应明显等问题。葛根素是从野葛中提取的异黄酮类活性成分，可通过减轻氧化应激和炎性损伤、抗心律失常、抗心肌纤维化、减轻心肌程序性死亡、调节脂质代谢、改善线粒体功能保护心血管。总结了葛根素治疗心血管疾病的药理作用研究进展，为葛根素的研究和临床应用提供参考。

In recent years, the number of patients with cardiovascular diseases in China has continued to rise. Currently, there are some patients who are intolerant to commonly used therapeutic drugs in clinical practice, and there are obvious long-term adverse reactions to medication. Puerarin is flavonoid active ingredient from Pueraria lobate (Willd.) Ohwi. Puerarin can protect the cardiovascular system by reducing oxidative stress and inflammatory damage, anti-arrhythmic effects, anti-myocardial fibrosis, alleviating programmed cardiac death, regulating lipid metabolism, and improving mitochondrial function. This article summarizes the pharmacological research progress of puerarin in treatment of cardiovascular diseases, providing reference for the research and clinical application of puerarin.

R285.5;R972