目的 使用带式真空干燥机对穿虎祛痛颗粒浸膏进行干燥工艺优化。方法 将单因素实验法和响应面法结合，确定考察浸膏相对密度、履带速率、第2段加热温度和布料速度4个影响因素，并采用Hassan法对提取物干浸膏转移率和大黄素转移率进行归一化处理后的综合评分作为考察指标，优化穿虎祛痛提取物的带式真空干燥工艺。结果 优化后的工艺参数为相对密度1.26、履带速率110 mm/min，第2段加热温度95 ℃、布料速度1.7 L/h。结论 所得真空带式干燥工艺耗时短、效率高，工艺稳定，可操作性强，为穿虎祛痛颗粒提取物的干燥工艺研究提供支持。

Objective To optimize the drying process of Chuanhu Qutong Granules extract using belt vacuum drying process. Methods By combining single factor test method and response surface methodology, four influencing factors were determined to investigate the relative density of the extract, track speed, two-stage heating temperature, and fabric speed. The Hassan method was used to normalize the comprehensive scores of the dry extract transfer rate and emodin transfer rate as the evaluation indicators to optimize the belt vacuum drying process of Chuanhu Qutong extract. Results The optimized process parameters were relative extract density of 1.26, track speed of 110 mm/min, two-stage heating temperature of 95 ℃, and fabric speed of 1.7 L/h. Conclusion The vacuum belt drying process obtained has the advantages of short time consumption, high efficiency, stable process, and strong operability, providing support for the research on the drying process of Chuanhu Qutong Granules extract.

R284.2

泰山产业领军人才工程专项（tscx202507100）；山东省重点研发计划（竞争性创新平台）项目（2024CXPT074）