[关键词]
[摘要]
视网膜病变是糖尿病的主要微血管并发症,给患者的日常生活造成严重威胁。红景天苷可通过降低血糖水平、抑制视网膜细胞死亡、降低炎性损伤、减轻氧化应激损伤、抑制血管内皮生长因子的表达、减轻谷氨酸兴奋性毒性防治糖尿病视网膜病变。总结了红景天苷用于糖尿病视网膜病变的药理作用研究进展,为红景天苷的临床应用提供支持。
[Key word]
[Abstract]
Retinopathy is the main microvascular complication of diabetes, which poses a serious threat to the daily life of patient. Salidroside plays a role in preventing and treating diabetic retinopathy by lowering blood sugar levels, inhibiting retinal cell death, reducing inflammatory damage, reducing oxidative stress damage, inhibiting VEGF expression, and reducing glutamate excitotoxicity. This article summarizes the research progress on pharmacological effects of salidroside in diabetes retinopathy, and provides support for the clinical application of salidroside.
[中图分类号]
R988.1;R977
[基金项目]