乳腺癌是全球范围内严重威胁女性健康的恶性肿瘤，治疗的药物不良反应和耐药性是临床的重大挑战。蛇床子素可通过诱导肿瘤细胞凋亡、抑制肿瘤细胞侵袭和转移、抑制肿瘤增殖、降低耐药性发挥抗乳腺癌作用。总结了蛇床子素用于防治乳腺癌的研究，归纳了其作用机制，为蛇床子素治疗乳腺癌提供支持。

Breast cancer is a malignant tumor that seriously threatens women's health worldwide. Adverse drug reactions and drug resistance in treatment are major challenges in clinical practice. Osthole can play an anti-breast cancer role by inducing tumor cell apoptosis, inhibiting tumor cell invasion and metastasis, inhibiting tumor proliferation, and reducing drug resistance. This article summarizes the research progress on osthole in prevention and treatment of breast cancer, concludes their mechanisms, which provides support for treatment of breast cancer with osthole.

R286

成都市医学科研课题（2022632）