乳腺癌为女性常见恶性肿瘤之一，是导致女性癌症死亡的第2大恶性肿瘤，发病人群逐渐增多且呈年轻化趋势。乳腺癌的传统放化疗存在严重不良反应，限制了长期使用。黄芩素是由黄芩干燥根中提取的天然黄酮类成分，可通过抑制细胞增殖、阻滞肿瘤细胞侵袭和转移、促进细胞凋亡、逆转细胞耐药性发挥抗乳腺癌的作用。总结了黄芩素抗乳腺癌的研究进展，希望为乳腺癌的药物治疗提供参考。

Breast cancer is one of the common malignant tumors in women and the second leading cause of cancer death in women. The incidence is gradually increasing and is showing a trend of younger age. Traditional radiotherapy and chemotherapy for breast cancer have serious adverse reactions, which limit long-term use. Baicalin is a natural flavonoid component extracted from dried roots of Scutellariae Radix. Baicalein can play an anti-breast cancer role by inhibiting cell proliferation, limiting tumor cell invasion and metastasis, promoting cell apoptosis, and reversing cell resistance. This article summarizes the research progress of baicalein against breast cancer, hoping to provide a reference for drug therapy of breast cancer.

R979.1